Drometrizole trisiloxane

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Drometrizole Trisiloxane is a lipophilic benzotriazole derivative used in sunscreen to absorb ultraviolet radiation. It is marketed as Mexoryl XL by L'Oréal.

Etymology[edit | edit source]

The term "Drometrizole" is derived from the Greek word "dromeus" meaning "runner" and "trizo" meaning "to creak". "Trisiloxane" is derived from "tri" meaning "three", "silox" referring to the silicon-oxygen bond, and "ane" indicating a single bond.

Chemical Properties[edit | edit source]

Drometrizole Trisiloxane is a lipophilic benzotriazole derivative. It is an organic compound with the molecular formula C18H27N3O3Si. It is a yellowish powder with a slight odor. It is insoluble in water but soluble in oils and organic solvents.

Uses[edit | edit source]

The primary use of Drometrizole Trisiloxane is in sunscreens as a UV filter. It absorbs both UVA and UVB radiation, helping to protect the skin from sun damage. It is often combined with other UV filters to provide broad-spectrum protection. It is marketed under the brand name Mexoryl XL by L'Oréal.

Safety[edit | edit source]

Drometrizole Trisiloxane has been approved for use in sunscreens in many countries, including the European Union and Canada. However, it is not currently approved for use in the United States by the Food and Drug Administration (FDA). Studies have shown that it is a low-risk ingredient for skin irritation or allergy.

Related Terms[edit | edit source]

Drometrizole trisiloxane Resources
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Contributors: Prab R. Tumpati, MD