Drug-induced purpura

Drug-induced purpura is a condition characterized by the appearance of purple discolorations on the skin caused by bleeding underneath the skin after the consumption of certain medications. This condition is a type of purpura, a term that refers to purple-colored spots that are most often seen on the skin, the mucus membranes, and the surfaces of the organs.

Causes

Drug-induced purpura is caused by certain medications that may lead to a decrease in platelets, the blood cells responsible for clotting. These medications include nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and anticoagulants. Other drugs that can cause this condition include chemotherapy drugs, diuretics, and antidepressants.

Symptoms

The primary symptom of drug-induced purpura is the appearance of purple spots or patches on the skin. These spots may appear anywhere on the body but are most commonly seen on the legs and buttocks. Other symptoms may include bruising, bleeding, and, in severe cases, anemia.

Diagnosis

Diagnosis of drug-induced purpura involves a thorough medical history and physical examination. The doctor may also order blood tests to check for a decrease in platelets and to rule out other conditions that may cause similar symptoms.

Treatment

Treatment for drug-induced purpura primarily involves discontinuing the medication that is causing the condition. In severe cases, the patient may require hospitalization and blood transfusions. It is important to consult with a healthcare provider before discontinuing any medication.

See also

• Purpura
• Thrombocytopenia
• Platelet

References

Drug-induced purpura Resources
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