Embramine
An overview of the antihistamine drug Embramine
Overview[edit | edit source]
Embramine is a first-generation antihistamine used primarily for the treatment of allergic reactions and symptoms associated with allergic rhinitis, such as sneezing, itching, and runny nose. As a member of the ethanolamine class of antihistamines, Embramine is known for its sedative properties, which can be both a therapeutic benefit and a side effect.
Pharmacology[edit | edit source]
Embramine works by blocking the action of histamine at the H1 receptor sites. Histamine is a chemical released by the body during an allergic reaction, and it is responsible for many of the symptoms associated with allergies. By inhibiting histamine's effects, Embramine helps alleviate these symptoms.
Mechanism of Action[edit | edit source]
The primary mechanism of action of Embramine involves competitive inhibition of the H1 receptors. This prevents histamine from binding to its receptors, thereby reducing the physiological effects such as vasodilation, increased vascular permeability, and sensory nerve stimulation that lead to allergy symptoms.
Pharmacokinetics[edit | edit source]
Embramine is well absorbed from the gastrointestinal tract and undergoes extensive first-pass metabolism in the liver. It is metabolized primarily by the cytochrome P450 enzyme system and is excreted in the urine. The drug has a relatively short half-life, which necessitates multiple doses throughout the day to maintain therapeutic levels.
Clinical Uses[edit | edit source]
Embramine is indicated for the relief of symptoms associated with:
Due to its sedative effects, Embramine is sometimes used as a mild sedative or sleep aid in patients with insomnia related to allergies.
Side Effects[edit | edit source]
Common side effects of Embramine include:
Less common but more serious side effects can include urinary retention, tachycardia, and confusion, particularly in the elderly.
Precautions[edit | edit source]
Patients should be advised about the sedative effects of Embramine, especially if they are required to drive or operate heavy machinery. Caution is also advised in patients with glaucoma, prostatic hypertrophy, or asthma.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
