Encainide

Encainide is a class 1c antiarrhythmic drug that was developed in the late 20th century. It was withdrawn from the market due to its proarrhythmic properties, which could potentially lead to fatal arrhythmias.

Mechanism of Action

Encainide works by blocking the fast inward sodium current, thereby slowing the rate of rise of the action potential. This results in a decrease in the conduction velocity of the heart's electrical impulses, which can help to control abnormal heart rhythms.

Uses

Encainide was primarily used to treat ventricular arrhythmias, such as ventricular tachycardia. However, due to its potential to cause fatal arrhythmias, it is no longer available for use.

Side Effects

The most serious side effect of encainide is its potential to cause fatal arrhythmias. Other side effects can include dizziness, nausea, and shortness of breath.

History

Encainide was developed in the late 20th century and was initially seen as a promising treatment for ventricular arrhythmias. However, it was withdrawn from the market after studies showed that it could potentially cause fatal arrhythmias.

See Also

• Antiarrhythmic drug
• Ventricular arrhythmia
• Ventricular tachycardia

Encainide Resources
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