Endogenous depression
Endogenous Depression is a subtype of major depressive disorder that is characterized by a persistent feeling of sadness or a lack of interest in outside stimuli. The term "endogenous" refers to the belief that the depression comes from within the body, perhaps of genetic origin, rather than from an external source.
Definition[edit]
Endogenous Depression is a type of depression thought to be caused by internal factors, such as genetic predisposition or a biochemical imbalance, rather than external factors like life events or psychological factors. It is often characterized by a lack of enjoyment in activities that were once pleasurable, persistent feelings of sadness, and a lack of motivation or energy.
Symptoms[edit]
The symptoms of endogenous depression are similar to those of other forms of depression and can include feelings of sadness, hopelessness, and a loss of interest in activities. Other symptoms can include changes in appetite, sleep disturbances, and difficulty concentrating. In severe cases, thoughts of suicide may also be present.
Causes[edit]
The exact cause of endogenous depression is unknown, but it is believed to be largely due to genetic factors. Research has shown that individuals with a family history of depression are more likely to develop the condition. Other factors, such as hormonal imbalances or changes in brain chemistry, may also play a role.
Treatment[edit]
Treatment for endogenous depression typically involves a combination of medication and psychotherapy. Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs), are commonly used. Psychotherapy, including cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT), can also be effective in treating endogenous depression.
See Also[edit]
References[edit]
Sponsored Health Resource

W8MD Weight Loss, Sleep & MedSpa
Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.
GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.
- Medical weight loss NYC
- Affordable GLP-1 injections NYC
- Budget GLP-1 weight loss shots Philadelphia
- New Jersey medical weight loss
- NYC medical weight loss blog
- Philadelphia weight loss blog
- Sleep medicine and sleep apnea services
- W8MD MedSpa and wellness
Book a W8MD appointment · View GLP-1 specials
Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian