Endogenous depression

From WikiMD's Wellness Encyclopedia

Endogenous Depression is a subtype of major depressive disorder that is characterized by a persistent feeling of sadness or a lack of interest in outside stimuli. The term "endogenous" refers to the belief that the depression comes from within the body, perhaps of genetic origin, rather than from an external source.

Definition[edit | edit source]

Endogenous Depression is a type of depression thought to be caused by internal factors, such as genetic predisposition or a biochemical imbalance, rather than external factors like life events or psychological factors. It is often characterized by a lack of enjoyment in activities that were once pleasurable, persistent feelings of sadness, and a lack of motivation or energy.

Symptoms[edit | edit source]

The symptoms of endogenous depression are similar to those of other forms of depression and can include feelings of sadness, hopelessness, and a loss of interest in activities. Other symptoms can include changes in appetite, sleep disturbances, and difficulty concentrating. In severe cases, thoughts of suicide may also be present.

Causes[edit | edit source]

The exact cause of endogenous depression is unknown, but it is believed to be largely due to genetic factors. Research has shown that individuals with a family history of depression are more likely to develop the condition. Other factors, such as hormonal imbalances or changes in brain chemistry, may also play a role.

Treatment[edit | edit source]

Treatment for endogenous depression typically involves a combination of medication and psychotherapy. Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs), are commonly used. Psychotherapy, including cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT), can also be effective in treating endogenous depression.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD