Endomysium

Endomysium is a type of connective tissue that surrounds individual muscle fibers, or myocytes. It is a component of the muscular system, and plays a crucial role in muscle function and structure.

Structure

The endomysium is composed of reticular fibers and is situated between individual muscle fibers in a muscle or muscle bundle. It contains capillaries, nerves, and lymphatic vessels that nourish the muscle fibers. The endomysium is continuous with the perimysium, the connective tissue that bundles muscle fibers together into fascicles, and the epimysium, the connective tissue that surrounds the entire muscle.

Function

The endomysium provides structural support to muscle fibers and helps to distribute the forces produced by muscle contraction. It also provides a pathway for the blood vessels and nerves that supply the muscle fibers. The endomysium, along with the perimysium and epimysium, contribute to the elasticity and contractility of muscles.

Clinical significance

Damage or disease affecting the endomysium can lead to muscle weakness and other symptoms. For example, in celiac disease, antibodies against the enzyme tissue transglutaminase cause an immune response that can damage the endomysium, leading to various symptoms including muscle weakness.

See also

• Muscular system
• Myocyte
• Perimysium
• Epimysium
• Celiac disease

References

Endomysium Resources
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