Enisamium iodide

Enisamium iodide

Enisamium iodide is an antiviral drug used in the treatment of influenza and other viral infections. It is a derivative of isonicotinic acid, and is also known as FAV00D.

Chemistry

Enisamium iodide is a quaternary ammonium compound with the chemical formula C12H16IN3O2. It is a white crystalline powder that is soluble in water and alcohol. The compound is stable under normal conditions, but can decompose under high heat or in the presence of strong acids or bases.

Mechanism of Action

Enisamium iodide works by inhibiting the replication of the influenza virus. It does this by interfering with the virus's RNA polymerase, an enzyme that is essential for the virus to copy its genetic material and multiply. By blocking this enzyme, enisamium iodide prevents the virus from spreading within the body.

Clinical Use

Enisamium iodide is used in the treatment of influenza A and B, as well as other viral infections. It is typically administered orally, either as a tablet or a liquid suspension. The drug is generally well tolerated, with side effects being rare and usually mild. These can include nausea, vomiting, and diarrhea.

Research and Development

Enisamium iodide was first synthesized in the 1970s, and has since been the subject of numerous clinical trials. Recent research has focused on its potential use in the treatment of other viral infections, including COVID-19. However, more studies are needed to confirm its efficacy and safety in these settings.

See Also

• Antiviral drug
• Influenza
• RNA polymerase
• COVID-19