Estradiol cypionate/medroxyprogesterone acetate
Estradiol cypionate/medroxyprogesterone acetate is a combination medication used in hormone replacement therapy (HRT) and contraception. It contains two active ingredients: estradiol cypionate, an estrogen, and medroxyprogesterone acetate, a progestin. This combination is designed to provide the benefits of both hormones while minimizing the risks associated with their individual use.
Medical Uses[edit | edit source]
Estradiol cypionate/medroxyprogesterone acetate is primarily used for:
- Hormone replacement therapy in postmenopausal women to alleviate symptoms such as hot flashes, vaginal atrophy, and osteoporosis.
- Contraception to prevent pregnancy.
Mechanism of Action[edit | edit source]
The combination works by:
- Estradiol cypionate: Mimicking the natural estrogen hormone, it helps in maintaining the female reproductive system and secondary sexual characteristics.
- Medroxyprogesterone acetate: Mimicking the natural progesterone hormone, it helps in regulating the menstrual cycle and maintaining the endometrium.
Side Effects[edit | edit source]
Common side effects may include:
Serious side effects can include:
Contraindications[edit | edit source]
This medication should not be used in individuals with:
Administration[edit | edit source]
Estradiol cypionate/medroxyprogesterone acetate is typically administered via intramuscular injection by a healthcare professional. The dosage and frequency depend on the specific condition being treated.
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Contributors: Prab R. Tumpati, MD
