FAM151A

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Genomic region of 3' end of gene FAM151A.pdf
FAM151A Expression in HPA RNA-seq normal tissues
Antibody staining of FAM151A in human kidney tissue.png
FAM151A predicted tertiary structure
Conservation of protein FAM151A

FAM151A is a protein that in humans is encoded by the FAM151A gene. This gene is a member of the FAM151 family, which is characterized by its conserved domain structure and sequence homology.

Function[edit | edit source]

The specific function of the FAM151A protein is not well understood. However, it is believed to play a role in various cellular processes due to its conserved nature across different species. The protein may be involved in cell signaling, cell adhesion, or other critical cellular functions.

Gene[edit | edit source]

The FAM151A gene is located on chromosome 22 in humans. It consists of multiple exons and introns, and its expression is regulated by various transcription factors. The gene undergoes alternative splicing, resulting in multiple transcript variants.

Expression[edit | edit source]

FAM151A is expressed in various tissues, with higher expression levels observed in certain brain regions, suggesting a potential role in neurodevelopment or neurophysiology. The expression pattern of FAM151A can be studied using techniques such as RT-PCR, Western blotting, and immunohistochemistry.

Clinical Significance[edit | edit source]

Mutations or dysregulation of the FAM151A gene may be associated with certain genetic disorders or diseases. However, more research is needed to fully understand its clinical implications. Studies are ongoing to determine the potential link between FAM151A and specific pathologies.

Research[edit | edit source]

Current research on FAM151A includes investigating its role in cellular pathways, its interaction with other proteins, and its potential involvement in disease mechanisms. Model organisms, such as mice and zebrafish, are often used to study the gene's function and its impact on development and disease.

See Also[edit | edit source]

References[edit | edit source]

Template:Gene-3D


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Contributors: Prab R. Tumpati, MD