FGF3

FGF3 or Fibroblast Growth Factor 3 is a protein that in humans is encoded by the FGF3 gene. It is a member of the fibroblast growth factor (FGF) family, which is involved in a variety of biological processes.

Function

FGF3 is a key molecule in the development of the inner ear and the nervous system. It plays a crucial role in the formation of the midbrain and the cerebellum, as well as in the development of the ear and eye. It is also involved in the regulation of cell growth, cell differentiation, and cell migration.

Clinical significance

Mutations in the FGF3 gene are associated with Michel aplasia, a rare congenital malformation characterized by the absence of the inner ear. It is also associated with LADD syndrome, a genetic disorder that affects many parts of the body, including the ears, teeth, and sweat glands.

See also

• Fibroblast growth factor
• FGF family
• Michel aplasia
• LADD syndrome

External links

• GeneCards - FGF3

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