Fibroblast growth factor receptor 2
(Redirected from FGFR2)
A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the mesenchyme and is activated by fibroblast growth factor 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in epithelial cells and is activated by fibroblast growth factor 7 and fibroblast growth factor 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., Apert syndrome; and Crouzon syndrome).
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Contributors: Prab R. Tumpati, MD
