Famprofazone
Famprofazone[edit | edit source]
Famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that is used for its analgesic and antipyretic properties. It is a prodrug that is metabolized in the body to produce methamphetamine and amphetamine, which contribute to its effects.
Pharmacology[edit | edit source]
Famprofazone is classified as a prodrug, meaning it is inactive in its administered form and requires metabolic conversion to become active. Once ingested, famprofazone is metabolized by the liver into its active components, including methamphetamine and amphetamine. These metabolites are responsible for the drug's analgesic and stimulant effects.
The presence of methamphetamine and amphetamine as metabolites can lead to positive results in drug tests for these substances, which is an important consideration for patients who may be subject to such testing.
Medical Uses[edit | edit source]
Famprofazone is primarily used for the relief of mild to moderate pain and to reduce fever. It is often prescribed for conditions such as arthritis, musculoskeletal pain, and other inflammatory conditions. Its effectiveness in pain relief is due to its ability to inhibit the synthesis of prostaglandins, which are compounds involved in the inflammatory response.
Side Effects[edit | edit source]
As with other NSAIDs, famprofazone can cause a range of side effects. Common side effects include gastrointestinal issues such as nausea, vomiting, and stomach pain. More serious side effects can include gastrointestinal bleeding, hypertension, and renal impairment.
The presence of methamphetamine and amphetamine as metabolites also raises concerns about potential abuse and addiction, as these substances are known for their stimulant effects.
Contraindications[edit | edit source]
Famprofazone should not be used in individuals with a history of substance abuse, particularly with stimulants. It is also contraindicated in patients with severe cardiovascular disease, hypertension, or renal impairment.
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
