Fenbendazole
Fenbendazole is a broad spectrum broad-spectrum anthelmintic drug that is used to prevent or eliminate a variety of parasitic infections in animals. It is part of the benzimidazole class of anthelmintics and is commonly used in both veterinary and human medicine.
Etymology[edit | edit source]
The term "Fenbendazole" is derived from the chemical structure of the drug, which includes a phenyl group (represented by "Fen"), a benzene ring (represented by "ben"), and a imidazole ring (represented by "dazole").
Pharmacology[edit | edit source]
Fenbendazole works by inhibiting the polymerization of tubulin into microtubules, which are essential for the uptake of glucose in parasites. This leads to the depletion of energy stores and ultimately the death of the parasite.
Uses[edit | edit source]
Fenbendazole is used to treat a variety of parasitic infections, including nematodes, cestodes, and giardia. It is also used in the treatment of certain types of cancer due to its ability to inhibit the growth of rapidly dividing cells.
Side Effects[edit | edit source]
Common side effects of Fenbendazole include nausea, vomiting, and diarrhea. In rare cases, it can cause bone marrow suppression, leading to a decrease in white blood cell count.
Related Terms[edit | edit source]
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Contributors: Prab R. Tumpati, MD