Filtration fraction
Filtration Fraction is a term used in Nephrology to describe the proportion of the renal plasma flow that is filtered by the kidney. It is a key concept in understanding the function of the kidney and its role in maintaining homeostasis in the body.
Definition[edit | edit source]
The Filtration Fraction (FF) is defined as the ratio of the Glomerular Filtration Rate (GFR) to the Renal Plasma Flow (RPF). It is usually expressed as a percentage and typically ranges from 15% to 20% in a healthy individual.
Formula[edit | edit source]
The formula for calculating the Filtration Fraction is:
FF = GFR / RPF
Where:
- GFR is the Glomerular Filtration Rate, which measures the amount of blood filtered by the glomeruli per minute.
- RPF is the Renal Plasma Flow, which measures the volume of plasma that reaches the kidneys per minute.
Clinical Significance[edit | edit source]
The Filtration Fraction is an important parameter in assessing kidney function. Changes in the Filtration Fraction can indicate various kidney diseases and conditions. For example, a decreased Filtration Fraction may indicate glomerulonephritis, while an increased Filtration Fraction may suggest renal artery stenosis.
See Also[edit | edit source]
References[edit | edit source]
- Smith, H.W. (1951). The Kidney: Structure and Function in Health and Disease. Oxford University Press, New York.
- Brenner, B.M., Rector, F.C. (2008). Brenner and Rector's The Kidney, 8th ed. Saunders Elsevier, Philadelphia.
Filtration fraction Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD