Fluproquazone
A non-steroidal anti-inflammatory drug
| Fluproquazone | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Fluproquazone is a non-steroidal anti-inflammatory drug (NSAID) that was developed for the treatment of pain and inflammation. It is part of the quinazolinone class of compounds and has been studied for its analgesic and anti-inflammatory properties.
Chemical Structure[edit | edit source]
Fluproquazone is characterized by its quinazolinone core structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrimidine ring. This structure is common among several pharmaceutical agents with anti-inflammatory activity.
Mechanism of Action[edit | edit source]
Fluproquazone, like other NSAIDs, works by inhibiting the activity of cyclooxygenase (COX) enzymes. These enzymes are responsible for the conversion of arachidonic acid into prostaglandins, which are mediators of inflammation and pain. By reducing the production of prostaglandins, fluproquazone helps to alleviate symptoms associated with inflammatory conditions.
Pharmacokinetics[edit | edit source]
The pharmacokinetic profile of fluproquazone includes its absorption, distribution, metabolism, and excretion. After oral administration, fluproquazone is absorbed into the bloodstream and distributed throughout the body. It undergoes hepatic metabolism and is primarily excreted via the kidneys.
Clinical Use[edit | edit source]
Fluproquazone has been used in the management of various conditions associated with pain and inflammation, such as arthritis and musculoskeletal disorders. Its efficacy in reducing pain and improving function in these conditions has been evaluated in clinical trials.
Side Effects[edit | edit source]
As with other NSAIDs, fluproquazone may cause side effects, including gastrointestinal disturbances, such as gastritis and peptic ulcer disease, as well as renal and cardiovascular effects. Patients are advised to use this medication under medical supervision, especially if they have pre-existing conditions that may be exacerbated by NSAID use.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
