Fructooligosaccharide

From WikiMD.com Medical Encyclopedia

A type of carbohydrate composed of short chains of fructose molecules


Structural formula of a fructooligosaccharide

Fructooligosaccharides (FOS) are a type of oligosaccharide, which are carbohydrates composed of short chains of fructose molecules. These compounds are found naturally in many plants, including onions, garlic, bananas, wheat, and asparagus. FOS are used as an alternative sweetener and are known for their prebiotic effects, promoting the growth of beneficial gut microbiota.

Structure and Composition[edit | edit source]

FOS consist of linear chains of fructose units, typically ranging from 2 to 10 fructose molecules, which are linked by β(2→1) glycosidic bonds. The chain may terminate with a glucose unit, forming a kestose structure. The general formula for FOS is GFn, where G is a glucose unit and Fn represents the number of fructose units.

Sources[edit | edit source]

FOS are naturally present in a variety of plants. Some of the richest sources include:

Health Benefits[edit | edit source]

FOS are considered prebiotics, which means they stimulate the growth and activity of beneficial bacteria in the colon. These bacteria, such as Bifidobacteria and Lactobacilli, play a crucial role in maintaining gut health and enhancing the immune system. The consumption of FOS has been associated with several health benefits, including:

Uses[edit | edit source]

FOS are used in the food industry as a low-calorie sweetener and as a functional ingredient to improve the texture and taste of food products. They are commonly added to:

Mechanism of Action[edit | edit source]

Once ingested, FOS pass through the upper gastrointestinal tract undigested and reach the colon, where they are fermented by the gut microbiota. This fermentation process produces short-chain fatty acids, such as butyrate, propionate, and acetate, which provide energy to colonocytes and have various health-promoting effects.

Potential Side Effects[edit | edit source]

While FOS are generally considered safe, excessive consumption can lead to gastrointestinal discomfort, including bloating, gas, and diarrhea. It is recommended to gradually increase the intake of FOS to allow the gut microbiota to adapt.

Related Pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD