Fusobacterium necrophorum

Fusobacterium necrophorum is a species of bacteria that is part of the normal flora in the human oropharynx, gastrointestinal tract, and female genital tract. It is an anaerobic, gram-negative bacterium, and is known to cause a variety of diseases in humans, including Lemierre's syndrome, pharyngitis, and peritonsillar abscess.

Characteristics

Fusobacterium necrophorum is a non-spore-forming, non-motile bacterium. It is pleomorphic, meaning it can change its shape or size in response to changes in its environment. It is also a fermentative bacterium, producing butyric acid and isobutyric acid as end products of fermentation.

Pathogenesis

Fusobacterium necrophorum is an opportunistic pathogen, meaning it can cause disease when the host's defenses are compromised. It is known to cause a variety of diseases in humans, including Lemierre's syndrome, pharyngitis, and peritonsillar abscess. These diseases are often severe and can be life-threatening.

Treatment

Treatment for infections caused by Fusobacterium necrophorum typically involves antibiotics. The bacterium is usually susceptible to penicillin, metronidazole, and clindamycin. In severe cases, surgical intervention may be necessary.

See also

• Fusobacterium
• Lemierre's syndrome
• Pharyngitis
• Peritonsillar abscess