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Garrod's pads are non-tender, firm nodules that are found over the dorsal aspect of the distal interphalangeal joints in patients with rheumatoid arthritis. They were first described by the British physician Archibald Garrod in the late 19th century.

History

Archibald Garrod, a British physician, first described these nodules in the late 19th century. Garrod's work primarily focused on genetics and biochemistry, but he also made significant contributions to the field of rheumatology, including the discovery of Garrod's pads.

Pathophysiology

Garrod's pads are caused by synovial hypertrophy and fibrosis, which leads to the formation of firm nodules over the distal interphalangeal joints. These nodules are typically non-tender and do not cause any discomfort to the patient. However, they can be a sign of underlying rheumatoid arthritis, a chronic inflammatory disorder that can affect various joints in the body.

Clinical significance

Garrod's pads are a clinical sign of rheumatoid arthritis. They are typically found in patients who have had the disease for a long period of time. The presence of these nodules can help physicians diagnose rheumatoid arthritis in patients who present with joint pain and stiffness.

Treatment

There is no specific treatment for Garrod's pads. Instead, treatment is focused on managing the underlying rheumatoid arthritis. This can include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs). In severe cases, surgical intervention may be necessary.

See also

• Rheumatoid arthritis
• Archibald Garrod
• Distal interphalangeal joints
• Synovial hypertrophy