Glucophage xr
Extended-release formulation of the drug Metformin
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Glucophage XR is an extended-release formulation of the drug Metformin, which is commonly used in the management of type 2 diabetes. The XR in Glucophage XR stands for "extended-release," indicating that the medication is designed to be released slowly over time to provide a more consistent therapeutic effect.
Medical Uses[edit | edit source]
Glucophage XR is primarily prescribed for the treatment of type 2 diabetes mellitus. It helps to control blood sugar levels by improving the body's sensitivity to insulin and decreasing the amount of glucose produced by the liver. It is often used in conjunction with diet and exercise to improve glycemic control.
Mechanism of Action[edit | edit source]
The active ingredient in Glucophage XR, Metformin, works by:
- Decreasing hepatic glucose production
- Decreasing intestinal absorption of glucose
- Improving insulin sensitivity by increasing peripheral glucose uptake and utilization
Dosage and Administration[edit | edit source]
Glucophage XR is taken orally, usually once daily with the evening meal. The dosage is individualized based on the patient's medical condition, response to treatment, and other medications they may be taking. It is important to follow the prescribed dosage and not to crush or chew the extended-release tablets.
Side Effects[edit | edit source]
Common side effects of Glucophage XR include:
- Gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain
- Lactic acidosis, a rare but serious condition, especially in patients with renal impairment or other risk factors
Contraindications[edit | edit source]
Glucophage XR is contraindicated in patients with:
- Severe renal impairment
- Known hypersensitivity to Metformin
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Related Pages[edit | edit source]
Categories[edit | edit source]
| Diabetes Drug Stub | |
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| This article about a diabetes drug is a stub. You can help WikiMD by expanding it. | |
| Related topics | Diabetes mellitus · Insulin · Hypoglycemia · Hyperglycemia |
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