Glucoraphanin

From WikiMD's Food, Medicine & Wellness Encyclopedia

Glucoraphanin is a glucosinolate that is found in cruciferous vegetables, most notably in broccoli and broccoli sprouts. It is a natural compound that is known for its potential health benefits, including its role in cancer prevention and its anti-inflammatory properties.

Chemical Structure[edit | edit source]

Glucoraphanin is a sulfur-containing compound. Its chemical structure consists of a glucose molecule attached to a sulforaphane molecule. The glucose molecule is attached to the sulforaphane molecule via a sulfur bond, which is broken down by the enzyme myrosinase to release sulforaphane.

Health Benefits[edit | edit source]

Glucoraphanin is converted into sulforaphane by the enzyme myrosinase, which is released when the plant cells are damaged, such as when the vegetable is chopped or chewed. Sulforaphane is a potent antioxidant and detoxifier, and it has been shown to have anti-cancer properties.

Cancer Prevention[edit | edit source]

Several studies have suggested that glucoraphanin may help to prevent cancer. It does this by inducing the body's own protective enzymes, which detoxify carcinogens. This process is known as phase II enzyme induction.

Anti-Inflammatory Properties[edit | edit source]

Glucoraphanin also has anti-inflammatory properties. It has been shown to inhibit the production of pro-inflammatory cytokines, which are proteins that promote inflammation.

Dietary Sources[edit | edit source]

The primary dietary source of glucoraphanin is broccoli and broccoli sprouts. Other cruciferous vegetables, such as kale, cabbage, and Brussels sprouts, also contain glucoraphanin, but in smaller amounts.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD