Glutamate-rich protein 3

Human protein and gene

Glutamate-rich protein 3 (ERICH3) is a protein encoded by the ERICH3 gene in humans. This protein is characterized by its high content of glutamate residues and is involved in various cellular processes.

Structure

Structure of ERICH3 isoforms

The ERICH3 protein is composed of multiple isoforms, which arise from alternative splicing of the ERICH3 gene. These isoforms vary in their amino acid sequences and functional domains. The protein is rich in glutamate residues, which are thought to contribute to its functional properties.

Function

ERICH3 is implicated in several cellular functions, although its precise roles are not fully understood. The protein is believed to be involved in cell signaling pathways and may play a role in the regulation of neurotransmitter systems. Its glutamate-rich regions suggest a potential interaction with other proteins or cellular components that are sensitive to glutamate residues.

Genetic Information

The ERICH3 gene is located on chromosome 1 in humans. It is expressed in various tissues, with notable expression in the brain, suggesting a role in neurological functions. The gene undergoes alternative splicing, resulting in multiple transcript variants that encode different protein isoforms.

Clinical Significance

Domains of ERICH3 protein

Mutations or variations in the ERICH3 gene have been studied in the context of psychiatric disorders and neurological diseases. Research is ongoing to determine the exact implications of these genetic variations and their potential impact on human health.

Research Directions

Current research is focused on elucidating the specific functions of ERICH3 in the brain and other tissues. Studies are also investigating the potential link between ERICH3 and various mental health conditions, aiming to understand how alterations in this protein might contribute to disease mechanisms.

Related pages

• Glutamate receptor
• Neurotransmitter
• Chromosome 1
• Protein structure