Gonadotropic hormone
Gonadorelin Acetate is a synthetic version of gonadotropin-releasing hormone (GnRH) used in the diagnosis and treatment of certain hormonal disorders. It is a decapeptide, meaning it is composed of ten amino acids. Gonadorelin Acetate is marketed under various brand names including Factrel, Lutrepulse and Kryptocur among others.
Medical Uses[edit | edit source]
Gonadorelin Acetate is used in the diagnosis of hypogonadism, a condition characterized by low sex hormone production. It is also used in the treatment of delayed puberty, infertility, and certain types of breast cancer.
Mechanism of Action[edit | edit source]
Gonadorelin Acetate works by stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are essential for normal growth, sexual development, and reproduction.
Side Effects[edit | edit source]
Common side effects of Gonadorelin Acetate include headache, nausea, and vomiting. More serious side effects may include allergic reactions, chest pain, and irregular heartbeat.
Pharmacokinetics[edit | edit source]
After administration, Gonadorelin Acetate is rapidly absorbed and distributed throughout the body. It is metabolized in the liver and excreted in the urine.
History[edit | edit source]
Gonadorelin Acetate was first synthesized in the 1970s. It was approved for medical use in the United States in 1978.
See Also[edit | edit source]
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