HC-067047

HC-067047 is a potent and selective inhibitor of the TRPV4 ion channel. It is used in scientific research to help understand the role of TRPV4 in various biological processes and diseases.

Overview[edit | edit source]

HC-067047 is a small molecule that selectively inhibits the TRPV4 ion channel. TRPV4 is a member of the Transient Receptor Potential (TRP) family of ion channels, which are involved in a wide range of physiological processes. HC-067047 is used in research to help understand the role of TRPV4 in these processes and in various diseases.

Mechanism of Action[edit | edit source]

HC-067047 works by binding to the TRPV4 ion channel and blocking its activity. This prevents the flow of ions through the channel, which can affect various cellular processes. The exact mechanism by which HC-067047 inhibits TRPV4 is not fully understood, but it is thought to involve a direct interaction with the channel protein.

Uses in Research[edit | edit source]

HC-067047 is used in research to study the role of TRPV4 in various biological processes and diseases. For example, it has been used to investigate the role of TRPV4 in pain perception, inflammation, and cardiovascular function. It has also been used to study the potential therapeutic benefits of TRPV4 inhibition in conditions such as cystic fibrosis, pulmonary edema, and certain types of cancer.

Safety and Toxicity[edit | edit source]

As a research tool, HC-067047 is not intended for human consumption. However, studies in animals have shown that it is generally well tolerated at the doses typically used in research. The potential toxicity of HC-067047 in humans is not known.