HLA-B62
HLA-B62 is a human leukocyte antigen (HLA) serotype. The HLA system is a group of genes that are crucial for the function of the immune system. HLA-B62 is a broad antigen serotype that is further divided into HLA-B15 and HLA-B40 split antigen serotypes.
Structure and Function[edit | edit source]
HLA-B62 is a cell surface protein that is encoded by the B locus of the Major Histocompatibility Complex (MHC) on chromosome 6. It plays a vital role in the immune system's recognition and response to foreign antigens. The protein is composed of a heavy chain and a light chain, which together form a groove for peptide binding. This peptide-MHC complex is then presented to T cells, triggering an immune response.
Clinical Significance[edit | edit source]
HLA-B62 has been associated with various autoimmune and infectious diseases. For instance, it has been linked to an increased risk of rheumatoid arthritis, celiac disease, and certain types of cancer. It is also involved in the immune response to infections such as HIV and hepatitis C.
See Also[edit | edit source]
References[edit | edit source]
Translate: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD