HOXB9
HOXB9 is a gene that belongs to the homeobox family of genes. The protein encoded by this gene is a transcription factor that plays a crucial role in embryonic development and cell differentiation.
Function[edit | edit source]
The HOXB9 gene is part of the HOX gene family, which is a group of genes that play a vital role in the development of the body plan of an organism. These genes are responsible for determining the basic structure and orientation of an organism's body. The HOXB9 gene, in particular, is involved in the development of the spinal cord and ribs.
Clinical Significance[edit | edit source]
Alterations in the HOXB9 gene have been associated with various types of cancer, including breast cancer, lung cancer, and colorectal cancer. Overexpression of HOXB9 has been found to promote tumor growth and metastasis, making it a potential target for cancer therapy.
Research[edit | edit source]
Research into the HOXB9 gene is ongoing, with scientists exploring its role in cancer development and progression. Understanding the function of this gene could lead to new treatments for cancer and other diseases.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
