HOXD10

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HOXD10 is a gene that belongs to the homeobox family of genes. The protein encoded by this gene is a transcription factor that plays a crucial role in the development of the vertebrate body plan.

Function[edit | edit source]

The HOXD10 gene is part of the Hox gene family, a group of genes that are essential for the proper formation of the body structure during early embryonic development. These genes encode proteins that bind to specific DNA sequences, thereby controlling the activity (transcription) of other genes. In particular, the HOXD10 protein is involved in the development of the limbs and the vertebral column.

Clinical significance[edit | edit source]

Mutations in the HOXD10 gene have been associated with several medical conditions. For instance, alterations in this gene have been linked to hand-foot-genital syndrome, a rare disorder characterized by limb and genital abnormalities. Additionally, some studies suggest that HOXD10 may play a role in the progression of certain types of cancer, including breast cancer and colorectal cancer.

Research[edit | edit source]

Research on the HOXD10 gene is ongoing, with scientists aiming to better understand its function and its role in disease. This could potentially lead to the development of new therapeutic strategies for conditions associated with mutations in this gene.

See also[edit | edit source]

References[edit | edit source]


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