Hantaan orthohantavirus

Hantaan orthohantavirus (HTNV) is a species of virus in the genus Orthohantavirus. It is the causative agent of Korean hemorrhagic fever in humans, a disease endemic to Eastern Asia, particularly Korea and China. The virus is named after the Hantan River area in South Korea where it was first isolated.

Transmission

HTNV is primarily transmitted to humans through the inhalation of aerosolized urine, feces, and saliva of infected rodents, particularly the striped field mouse (Apodemus agrarius). Direct contact with these materials and rodent bites can also result in transmission.

Symptoms

The symptoms of HTNV infection include fever, hemorrhage, and kidney failure. The disease has a fatality rate of approximately 10%.

Treatment

There is currently no specific treatment or vaccine for HTNV. Treatment is supportive and includes fluid replacement, hemodialysis for kidney failure, and blood transfusion for severe hemorrhage.

Prevention

Prevention of HTNV infection involves avoiding contact with rodents and their droppings, and maintaining clean living and working environments.

See also

• Hantavirus
• Hantavirus pulmonary syndrome
• Hemorrhagic fever with renal syndrome

References

Hantaan orthohantavirus Resources
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