Hemostatic Powder Spray TC-325

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Hemostatic Powder Spray TC-325 is a medical device used in the management of bleeding in patients with gastrointestinal disorders. It is a hemostatic agent that works by forming a mechanical barrier over the bleeding site, promoting blood clotting and stopping the bleeding.

Mechanism of Action[edit | edit source]

The Hemostatic Powder Spray TC-325 is composed of a hydrophilic powder that rapidly absorbs water from blood to form a gel-like substance. This substance adheres to the bleeding site and forms a mechanical barrier that aids in the cessation of bleeding. The powder also concentrates platelets and clotting factors at the bleeding site, which further promotes hemostasis.

Indications[edit | edit source]

Hemostatic Powder Spray TC-325 is indicated for use in patients with active upper and lower gastrointestinal bleeding. This includes patients with peptic ulcer disease, gastric varices, Mallory-Weiss syndrome, and angiodysplasia. It can also be used in patients with bleeding after endoscopic procedures.

Contraindications[edit | edit source]

The use of Hemostatic Powder Spray TC-325 is contraindicated in patients with known hypersensitivity to any of the components of the powder. It is also not recommended for use in patients with severe coagulopathy or those who are at risk of aspiration.

Side Effects[edit | edit source]

The most common side effects of Hemostatic Powder Spray TC-325 include nausea, vomiting, and abdominal pain. Rarely, it can cause allergic reactions, respiratory distress, and bowel obstruction.

Clinical Trials[edit | edit source]

Several clinical trials have demonstrated the efficacy and safety of Hemostatic Powder Spray TC-325 in the management of gastrointestinal bleeding. These trials have shown that the device is effective in achieving hemostasis in a majority of patients, with a low rate of rebleeding. Template:Medical device

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Contributors: Prab R. Tumpati, MD