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Hepatic Failure
Hepatic failure, also known as liver failure, is a condition characterized by the loss of liver function. It can occur rapidly (acute) or over a period of time (chronic). The liver plays a crucial role in the body, including detoxification of harmful substances, protein synthesis, and production of biochemicals necessary for digestion.
Causes[edit | edit source]
Hepatic failure can be caused by a variety of factors. These include hepatitis, cirrhosis, alcoholism, and overdose of certain medications such as acetaminophen. Other less common causes include autoimmune hepatitis, Wilson's disease, and Budd-Chiari syndrome.
Symptoms[edit | edit source]
Symptoms of hepatic failure can vary depending on whether the condition is acute or chronic. Common symptoms include jaundice, fatigue, nausea, and abdominal pain. In severe cases, hepatic failure can lead to encephalopathy, which can cause confusion, drowsiness, and even coma.
Diagnosis[edit | edit source]
Diagnosis of hepatic failure typically involves a combination of medical history, physical examination, and laboratory tests. These tests may include blood tests to measure liver function, imaging tests such as an ultrasound or CT scan, and in some cases, a liver biopsy.
Treatment[edit | edit source]
Treatment for hepatic failure depends on the underlying cause and the severity of the condition. In some cases, liver function may be restored with medical treatment. In severe cases, a liver transplant may be necessary.
Prognosis[edit | edit source]
The prognosis for hepatic failure varies widely depending on the cause and severity of the condition, as well as the patient's overall health. With appropriate treatment, some patients can recover completely, while others may experience long-term complications or require a liver transplant.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD