Hexacyclonate

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Hexacyclonate is a sedative and anticonvulsant drug that belongs to the cyclopyrrolone family of drugs. It is also known by its trade name, Cyclonarol. Hexacyclonate is primarily used in the treatment of anxiety and insomnia.

Pharmacology[edit | edit source]

Hexacyclonate acts as a GABA_A receptor positive allosteric modulator. This means it enhances the effect of the neurotransmitter GABA on the GABA_A receptor, which results in sedative, anticonvulsant, anxiolytic, and muscle relaxant effects.

Medical Uses[edit | edit source]

Hexacyclonate is used in the treatment of conditions such as anxiety and insomnia. It can also be used as a premedication before surgery to reduce anxiety and induce sedation.

Side Effects[edit | edit source]

Like other drugs in the cyclopyrrolone family, Hexacyclonate can cause side effects such as drowsiness, dizziness, and confusion. In rare cases, it can also cause paradoxical reactions such as agitation, irritability, aggression, and hallucinations.

See Also[edit | edit source]

Hexacyclonate Resources
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Contributors: Prab R. Tumpati, MD