Hippocampal sulcus

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Hippocampal Commissure

The Hippocampal Commissure (also known as the commissure of fornix, psalterium, or lyra) is a significant structure in the brain that connects the two hippocampi, which are integral to the limbic system and play crucial roles in memory and spatial navigation.

Anatomy[edit | edit source]

The hippocampal commissure is located in the ventricular system of the brain, specifically within the third ventricle. It is a part of the larger fornix structure, which is a bundle of nerve fibers that carry signals from the hippocampus to the mammillary bodies and then to the anterior thalamic nuclei.

Function[edit | edit source]

The primary function of the hippocampal commissure is to facilitate communication between the two hippocampi. This communication is essential for the consolidation of long-term memory, as well as for spatial memory and navigation. The hippocampal commissure also plays a role in seizure propagation, particularly in temporal lobe epilepsy.

Clinical Significance[edit | edit source]

Abnormalities or damage to the hippocampal commissure can lead to a variety of neurological and psychiatric conditions. These include Alzheimer's disease, schizophrenia, and epilepsy. In particular, a reduced size of the hippocampal commissure has been associated with Alzheimer's disease and schizophrenia.

See Also[edit | edit source]

References[edit | edit source]


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