Hopantenic acid

Hopantenic acid (also known as Pantogam, Pantocalm, Pantogam Active) is a derivative of pantothenic acid (vitamin B5) and gamma-aminobutyric acid (GABA). It is a nootropic compound that is used in some countries for the treatment of various neurological conditions.

Chemistry[edit | edit source]

Hopantenic acid is a racemic mixture of two stereoisomers. It is a white crystalline powder that is soluble in water. The chemical formula of hopantenic acid is C9H17NO5.

Pharmacology[edit | edit source]

Hopantenic acid is believed to work by increasing the activity of the neurotransmitter GABA in the brain. GABA is an inhibitory neurotransmitter, which means it reduces the activity of neurons in the brain. This can have a calming effect and reduce symptoms of anxiety and other neurological conditions.

Medical uses[edit | edit source]

In some countries, hopantenic acid is used for the treatment of various neurological conditions, including epilepsy, cerebral palsy, and cognitive impairment. It is also used to improve memory and cognitive function in people with mild cognitive impairment or dementia.

Side effects[edit | edit source]

The most common side effects of hopantenic acid are nausea, vomiting, and diarrhea. Other side effects can include dizziness, headache, and insomnia.

Research[edit | edit source]

There is ongoing research into the potential benefits of hopantenic acid for various conditions, including Alzheimer's disease, Parkinson's disease, and stroke. However, more research is needed to confirm these potential benefits.