Hormone receptor

Hormone receptor

A hormone receptor is a receptor molecule that binds to a specific hormone. Hormone receptors are a wide family of proteins made up of receptors for thyroid and steroid hormones, retinoids and Vitamin D, and a variety of other receptors for various ligands, such as fatty acids and prostaglandins. There are two main classes of hormone receptors.

Classes of hormone receptors

Class I

The Class I hormone receptors are intracellular receptors that are located in the cytoplasm or nucleus.

Class II

The Class II hormone receptors are transmembrane receptors, which are embedded in the plasma membrane at the surface of the cell.

Function

Hormone receptors play a vital role in the function of the endocrine system. They receive signals from hormones and initiate a response from the cell. This process is known as signal transduction.

Clinical significance

Hormone receptors are relevant in the field of oncology because certain cancer cells have hormone receptors. In such cases, blocking the hormone receptor can help to slow down the growth of the tumor.

See also

• Endocrine system
• Hormone
• Signal transduction
• Oncology

References

Hormone receptor Resources
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