Ilepcimide

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Ilepcimide


Ilepcimide is a pharmaceutical drug used in the treatment of various mental disorders. It belongs to the class of antipsychotic drugs, specifically the phenothiazine class.

History[edit | edit source]

Ilepcimide was first synthesized in the mid-20th century, during a period of intense research into antipsychotic drugs. It was one of many phenothiazines developed during this time, a group of drugs that also includes chlorpromazine and thioridazine.

Pharmacology[edit | edit source]

Like other phenothiazines, ilepcimide works by blocking dopamine receptors in the brain. This reduces the activity of dopamine, a neurotransmitter that is often overactive in people with mental disorders such as schizophrenia and bipolar disorder.

Ilepcimide also has anticholinergic effects, meaning it blocks the action of acetylcholine, another neurotransmitter. This can help to reduce symptoms such as restlessness and agitation.

Clinical use[edit | edit source]

Ilepcimide is used in the treatment of a range of mental disorders, including schizophrenia, bipolar disorder, and severe anxiety. It can also be used to treat nausea and vomiting, particularly when these symptoms are caused by other medications.

Side effects[edit | edit source]

As with all antipsychotic drugs, ilepcimide can cause a range of side effects. These can include drowsiness, dry mouth, blurred vision, and constipation. In rare cases, it can also cause more serious side effects such as tardive dyskinesia, a condition characterized by involuntary movements of the face and body.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD