Influenza A virus subtype H5N6

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Influenza A virus subtype H5N6 is a subtype of the Influenza A virus that has been identified as a potential future pandemic threat. It is a subtype of the species Influenza A virus of the Orthomyxoviridae family of viruses.

Overview[edit | edit source]

The Influenza A virus subtype H5N6 is a subtype of viruses that causes influenza in birds and some mammals. It is a combination of several other avian influenza viruses. The subtype was first detected in 2014 and has since been identified in several countries, including China, Vietnam, and the Netherlands.

Structure and Composition[edit | edit source]

Like all Influenza A viruses, H5N6 is an Orthomyxovirus, with a genome composed of eight single-stranded negative-sense RNA segments. The H5N6 subtype is characterized by the hemagglutinin 5 (H5) and neuraminidase 6 (N6) proteins on its surface.

Pathogenesis[edit | edit source]

The H5N6 subtype is highly pathogenic in birds, causing severe disease and high mortality rates. In humans, the virus can cause severe respiratory illness, with symptoms including fever, cough, and shortness of breath. The virus is transmitted from birds to humans through direct contact with infected birds or their droppings, or indirectly through contaminated environments.

Prevention and Control[edit | edit source]

Prevention and control of H5N6 outbreaks in poultry are critical to reducing the risk of human infection. Measures include surveillance for early detection of outbreaks, culling of infected and exposed birds, and vaccination of poultry. In humans, antiviral drugs can be used for treatment and prophylaxis.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD