Influenza A virus subtype H3N2

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Influenza A virus subtype H3N2 is a subtype of viruses that causes influenza (flu). H3N2 viruses can infect birds and mammals. In birds, humans, and pigs, the virus has mutated into many strains. H3N2 is increasingly abundant in seasonal influenza, which occurs every year.

History[edit | edit source]

The H3N2 subtype was first identified in 1968 with the Hong Kong flu pandemic. It was the cause of the pandemic that killed an estimated one million people worldwide. Since then, it has led to regular epidemics of the flu.

Structure and Mechanism[edit | edit source]

The H3N2 virus is a subtype of Influenza A virus. The "H" refers to hemagglutinin, and the "N" refers to neuraminidase, both of which are key molecules on the surface of the virus that are responsible for its ability to infect host cells.

Epidemiology[edit | edit source]

H3N2 is one of the strains of Influenza A that is included in the annual flu vaccine. It is known for its ability to mutate rapidly, often rendering vaccines less effective.

Prevention and Treatment[edit | edit source]

Prevention of H3N2 is similar to the prevention of other strains of the flu. This includes getting the annual flu vaccine, practicing good hand hygiene, and avoiding close contact with those who are sick. Treatment typically involves rest, hydration, and over-the-counter medications to manage symptoms. In some cases, antiviral drugs may be used.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD