Interferon alfa

From WikiMD's Food, Medicine & Wellness Encyclopedia

Interferon alfa is a type of protein and antiviral or anticancer drug. It is a form of interferon, which are proteins released by the body's immune cells in response to viral infections. Interferon alfa is produced in a laboratory and used as a treatment for several types of cancer and hepatitis.

History[edit | edit source]

Interferon alfa was first identified in the late 1950s by two researchers, Alick Isaacs and Jean Lindenmann. They discovered that the body produces these proteins as a natural defense against viral infections. Since then, interferon alfa has been developed into a drug and used as a treatment for various diseases.

Medical uses[edit | edit source]

Interferon alfa is used to treat several types of cancer, including melanoma, kidney cancer, and certain types of leukemia and lymphoma. It is also used to treat hepatitis B and hepatitis C, two types of viral infections that affect the liver.

Mechanism of action[edit | edit source]

Interferon alfa works by stimulating the body's immune system to attack cancer cells or viral infections. It binds to specific receptors on the surface of cells, triggering a series of reactions that lead to the production of enzymes that inhibit virus replication. In cancer treatment, it can slow tumor growth and stimulate immune cells to attack cancer cells.

Side effects[edit | edit source]

Like all drugs, interferon alfa can cause side effects. The most common side effects are flu-like symptoms, including fever, chills, muscle aches, and fatigue. Other side effects can include depression, hair loss, and changes in blood counts.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD