Intermediate trophoblast

Intermediate trophoblast is a type of trophoblast that is intermediate in morphology and function between the cytotrophoblast and syncytiotrophoblast. It is found in the chorionic villi and extravillous trophoblast.

Morphology

The intermediate trophoblast is characterized by a large, round or polygonal shape with abundant eosinophilic cytoplasm. The nuclei are round to oval and have a coarse chromatin pattern with prominent nucleoli. The cells are often arranged in clusters or sheets.

Function

The intermediate trophoblast plays a crucial role in the invasion of the endometrium and the remodeling of the uterine spiral arteries. It also contributes to the formation of the placental bed and the chorionic villi.

Clinical significance

Abnormalities in the intermediate trophoblast can lead to various pregnancy-related disorders, such as preeclampsia, intrauterine growth restriction, and placental abruption. In addition, intermediate trophoblasts are the cells of origin for some types of gestational trophoblastic disease, including invasive mole and choriocarcinoma.

See also

• Trophoblast
• Cytotrophoblast
• Syncytiotrophoblast
• Chorionic villi
• Extravillous trophoblast
• Endometrium
• Uterine spiral arteries
• Placental bed
• Preeclampsia
• Intrauterine growth restriction
• Placental abruption
• Gestational trophoblastic disease
• Invasive mole
• Choriocarcinoma

Intermediate trophoblast Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski