Invasive hydatidiform mole

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Invasive hydatidiform mole is a rare form of gestational trophoblastic disease that invades the muscle layer of the uterus. It is a type of molar pregnancy and is characterized by the presence of hydatidiform mole tissue that grows into the muscles of the uterus.

Causes[edit | edit source]

Invasive hydatidiform mole is caused by an abnormal fertilization process. Instead of a normal pregnancy developing, a mass of abnormal tissue (a mole) grows in the uterus. This mole can invade the muscle layer of the uterus, leading to an invasive hydatidiform mole.

Symptoms[edit | edit source]

Symptoms of invasive hydatidiform mole may include vaginal bleeding, anemia, hyperemesis gravidarum (severe nausea and vomiting), and preeclampsia (high blood pressure and protein in the urine).

Diagnosis[edit | edit source]

Diagnosis of invasive hydatidiform mole is usually made through a combination of ultrasound imaging and blood tests to measure levels of human chorionic gonadotropin (hCG), a hormone produced by the placenta during pregnancy.

Treatment[edit | edit source]

Treatment for invasive hydatidiform mole typically involves surgery to remove the mole, followed by chemotherapy to kill any remaining abnormal cells.

Prognosis[edit | edit source]

With early detection and treatment, the prognosis for invasive hydatidiform mole is generally good. However, regular follow-up is necessary to monitor for potential complications, including the development of choriocarcinoma, a rare form of cancer.

See also[edit | edit source]

Invasive hydatidiform mole Resources
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Contributors: Prab R. Tumpati, MD