Intractable singultus

Intractable Singultus refers to a persistent and uncontrollable case of hiccups that lasts for an extended period, typically more than a month. Singultus, the medical term for hiccups, involves involuntary contractions of the diaphragm and the sudden closure of the vocal cords, which produces the characteristic "hic" sound. While most cases of hiccups are benign and resolve within a few minutes to hours, intractable singultus is a more serious condition that can lead to various complications, including sleep deprivation, weight loss, exhaustion, and even psychological distress.

Causes

Intractable singultus can be triggered by a variety of factors, which are often more complex than those causing short-term hiccups. These include:

• Gastrointestinal disorders such as gastroesophageal reflux disease (GERD) or intestinal obstruction
• Central nervous system disorders, including infections, tumors, or trauma
• Metabolic disorders like diabetes or kidney failure
• Psychogenic causes, including stress and anxiety

Diagnosis

Diagnosing intractable singultus involves a thorough medical history and physical examination, followed by various tests to identify any underlying conditions. These tests may include:

• Blood tests to check for infections, kidney function, and other possible metabolic causes
• Imaging studies such as X-rays, CT scans, or MRI scans to detect abnormalities in the diaphragm, lungs, and other organs
• Endoscopy to examine the esophagus and stomach for gastrointestinal issues

Treatment

Treatment for intractable singultus focuses on addressing the underlying cause, if identified. In cases where a specific cause cannot be found, treatment options may include:

• Medications such as muscle relaxants, anticonvulsants, or sedatives
• Nerve blocks or electrical stimulation of the phrenic nerve
• Surgical interventions in rare cases, such as diaphragm pacing

Prognosis

The outlook for individuals with intractable singultus varies depending on the underlying cause and the effectiveness of treatment. While some patients may experience relief with treatment, others may continue to suffer from persistent hiccups, impacting their quality of life.

See Also

• Hiccups
• Diaphragm (anatomy)
• Gastroesophageal reflux disease
• Central nervous system

Resources

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Intractable singultus for any updates.

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