Intralaminar thalamic nuclei

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Thalmus
Intralaminar thalamic nuclei
Details
Part ofThalamus
SystemCentral nervous system
ArteryThalamogeniculate artery
VeinThalamostriate vein
Identifiers
Latinnuclei intralaminares thalami
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FMA{{#property:P1402}}
Anatomical terms of neuroanatomy
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The intralaminar thalamic nuclei are a collection of nuclei located within the thalamus, a part of the diencephalon in the brain. These nuclei are situated within the internal medullary lamina, a sheet of white matter that divides the thalamus into its various components. The intralaminar nuclei play a crucial role in the modulation of consciousness, arousal, and pain perception.

Anatomy[edit | edit source]

The intralaminar thalamic nuclei are divided into several distinct nuclei, including:

These nuclei are interconnected with various regions of the cerebral cortex, basal ganglia, and other thalamic nuclei, facilitating their role in integrating and relaying information.

Function[edit | edit source]

The primary functions of the intralaminar thalamic nuclei include:

  • Modulation of consciousness and arousal: These nuclei are involved in maintaining alertness and wakefulness by projecting to the cerebral cortex and reticular activating system.
  • Pain perception: The intralaminar nuclei receive nociceptive (pain-related) information and are involved in the processing and perception of pain.
  • Motor control: Through connections with the basal ganglia, these nuclei play a role in the regulation of motor functions.

Clinical Significance[edit | edit source]

Damage or dysfunction of the intralaminar thalamic nuclei can result in various neurological conditions, including:

  • Thalamic pain syndrome: A condition characterized by chronic pain following a thalamic stroke.
  • Coma: Lesions in these nuclei can lead to a loss of consciousness.
  • Movement disorders: Disruption of the connections between the intralaminar nuclei and the basal ganglia can result in motor control issues.

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Contributors: Prab R. Tumpati, MD