Isomethadone
Isomethadone is a synthetic opioid that is chemically similar to methadone. It is used in the treatment of chronic pain and opioid dependence.
History[edit | edit source]
Isomethadone was first synthesized in the 1940s by the German pharmaceutical company Hoechst AG. It was developed as a potential alternative to morphine, which was in short supply during World War II.
Pharmacology[edit | edit source]
Isomethadone acts on the mu-opioid receptor, the primary site of action for most opioids. It is a full agonist, meaning it fully activates the receptor and produces a maximal response. This results in analgesia, sedation, and other effects characteristic of opioid drugs.
Medical uses[edit | edit source]
Isomethadone is used in the treatment of chronic pain and opioid dependence. It is often used as a second-line treatment when other opioids are not effective or are not tolerated.
Side effects[edit | edit source]
Like all opioids, isomethadone can cause a range of side effects. These can include nausea, vomiting, constipation, drowsiness, and respiratory depression. It can also cause physical dependence and withdrawal symptoms if stopped abruptly.
See also[edit | edit source]
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References[edit | edit source]
External links[edit | edit source]
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