Levomethadone

From WikiMD's Food, Medicine & Wellness Encyclopedia

Levomethadone is a synthetic opioid analgesic. It is the L-stereoisomer of methadone and is used in the treatment of opioid dependence and pain management.

Pharmacology[edit | edit source]

Levomethadone is a full agonist at the mu-opioid receptor and also has some activity at the NMDA receptor. It is metabolized in the liver and has a half-life of about 15-55 hours.

Medical uses[edit | edit source]

Levomethadone is used in the treatment of opioid dependence and for pain management. It is often used as a substitute for heroin in opioid replacement therapy.

Side effects[edit | edit source]

Common side effects of levomethadone include constipation, nausea, and drowsiness. More serious side effects can include respiratory depression and dependence.

See also[edit | edit source]

References[edit | edit source]


Levomethadone Resources
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Contributors: Prab R. Tumpati, MD