Isometheptene
Isometheptene is a vasoconstrictor used to treat migraine and cluster headaches. It is often combined with other medications, such as paracetamol (acetaminophen) or chlorpheniramine, and is sold under various brand names.
Pharmacology[edit | edit source]
Isometheptene works by constricting blood vessels in the brain, which helps to alleviate the pain of migraines and cluster headaches. It is believed to act on the serotonin system, although the exact mechanism of action is not fully understood.
Uses[edit | edit source]
Isometheptene is primarily used to treat migraines and cluster headaches. It is often used in combination with other medications, such as paracetamol or chlorpheniramine, to increase its effectiveness.
Side Effects[edit | edit source]
Common side effects of isometheptene include nausea, vomiting, and dizziness. In rare cases, it can cause serious side effects such as hypertension (high blood pressure), tachycardia (rapid heart rate), and ischemia (reduced blood flow to the heart).
Contraindications[edit | edit source]
Isometheptene is contraindicated in patients with coronary artery disease, hypertension, and hyperthyroidism. It should also not be used in patients who are pregnant or breastfeeding, due to the potential risk to the baby.
See Also[edit | edit source]
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