Keratosis punctata of the palmar creases

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Keratosis punctata of the palmar creases
Synonyms Punctate keratoderma
Pronounce N/A
Specialty Dermatology
Symptoms Small, hard keratotic plugs in the palmar creases
Complications N/A
Onset Usually in adulthood
Duration Chronic
Types N/A
Causes Genetic predisposition, environmental factors
Risks Family history, manual labor
Diagnosis Clinical diagnosis, skin biopsy
Differential diagnosis Palmoplantar keratoderma, eczema, psoriasis
Prevention N/A
Treatment Emollients, keratolytics, retinoids
Medication N/A
Prognosis N/A
Frequency Rare
Deaths N/A


Keratosis punctata of the palmar creases is a rare, autosomal dominant skin disorder. It is characterized by multiple, tiny "raindrop" keratoses, located predominantly on the palmar creases. The condition is also known as Keratosis punctata palmaris et plantaris.

Signs and Symptoms[edit | edit source]

The primary symptom of Keratosis punctata of the palmar creases is the presence of small, round, skin-colored papules that are located on the creases of the palms. These papules are typically 1-5mm in diameter and are often described as looking like "raindrops". They may also be present on the soles of the feet, but this is less common.

Causes[edit | edit source]

The exact cause of Keratosis punctata of the palmar creases is unknown. However, it is believed to be a genetic disorder, as it is often seen in multiple members of the same family. The condition is inherited in an autosomal dominant manner, meaning that an affected person has a 50% chance of passing the disorder on to each of their children.

Diagnosis[edit | edit source]

Diagnosis of Keratosis punctata of the palmar creases is typically made based on the characteristic appearance of the skin lesions. A skin biopsy may also be performed to confirm the diagnosis.

Treatment[edit | edit source]

There is currently no cure for Keratosis punctata of the palmar creases, and treatment is typically focused on managing the symptoms. This may include the use of topical creams or ointments to help soften the skin and reduce the appearance of the papules.

See Also[edit | edit source]

References[edit | edit source]

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