Laboratory animal allergy

Laboratory Animal Allergy (LAA) is a type of occupational allergy that affects individuals who work with laboratory animals. It is a significant occupational health concern in the biomedical research industry.

Causes

The primary cause of LAA is exposure to allergens present in the urine, dander, and saliva of laboratory animals. The most common animals that cause this allergy are rodents, particularly rats and mice. Other animals such as rabbits, guinea pigs, and cats can also cause LAA.

Symptoms

The symptoms of LAA are similar to those of other allergic reactions. They include rhinitis (runny nose), conjunctivitis (red, itchy eyes), asthma, and dermatitis (skin rash). In severe cases, LAA can lead to anaphylaxis, a potentially life-threatening allergic reaction.

Prevention and Management

Prevention and management of LAA involve reducing exposure to animal allergens. This can be achieved through the use of personal protective equipment (PPE), proper ventilation in animal facilities, and regular cleaning of animal cages and work areas. Immunotherapy may also be considered for individuals who continue to have symptoms despite these measures.

Impact

LAA can have a significant impact on the health and productivity of affected individuals. It can lead to absenteeism, reduced work efficiency, and in severe cases, it may force individuals to change their line of work.

See Also

• Occupational Asthma
• Allergen
• Immunotherapy

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