Large cell neuroendocrine carcinoma

From WikiMD's Food, Medicine & Wellness Encyclopedia

a usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.

Large cell neuroendocrine carcinoma Resources
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Contributors: Prab R. Tumpati, MD