Levonorgestrel cyclopropylcarboxylate
Synthetic progestogen
| Drug Information | |||
|---|---|---|---|
| Image | |||
| Identifiers
CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name |
Chemical Data
C H N O Molecular Weight | ||
Levonorgestrel cyclopropylcarboxylate is a synthetic progestogen derived from levonorgestrel. It is used in various hormonal contraceptives and has similar properties to other progestins.
Pharmacology[edit | edit source]
Levonorgestrel cyclopropylcarboxylate works by mimicking the effects of progesterone, a natural hormone involved in the menstrual cycle and pregnancy. It binds to progesterone receptors in the body, leading to changes in the endometrium and inhibition of ovulation.
Uses[edit | edit source]
This compound is primarily used in contraceptive formulations, including oral contraceptives, intrauterine devices, and implantable contraceptives. It is effective in preventing pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the endometrial lining.
Side Effects[edit | edit source]
Common side effects of levonorgestrel cyclopropylcarboxylate include nausea, headache, breast tenderness, and irregular menstrual bleeding. Serious side effects are rare but can include blood clots, stroke, and liver problems.
Mechanism of Action[edit | edit source]
Levonorgestrel cyclopropylcarboxylate acts by binding to progesterone receptors in the hypothalamus and pituitary gland, leading to decreased secretion of gonadotropins such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This suppression prevents the ovarian follicle from maturing and releasing an ovum.
Chemistry[edit | edit source]
The chemical structure of levonorgestrel cyclopropylcarboxylate includes a cyclopropyl group attached to the carboxylate moiety of levonorgestrel. This modification enhances its pharmacokinetic properties, making it more effective in its role as a contraceptive.
See Also[edit | edit source]
References[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
