Levopropoxyphene

From WikiMD's Wellnesspedia

Levopropoxyphene is a narcotic analgesic that is used in the treatment of pain. It is an opioid medication, and it works by changing the way the brain and nervous system respond to pain. Levopropoxyphene is the levorotatory stereoisomer of the synthetic opioid propoxyphene.

Pharmacology[edit | edit source]

Levopropoxyphene, like other opioids, acts on the mu-opioid receptors in the brain. It is a weak mu-opioid receptor agonist, and its analgesic effect is thought to be due to its conversion to norpropoxyphene, which is a more potent mu-opioid receptor agonist. Levopropoxyphene also has local anesthetic effects, which may contribute to its analgesic effect.

Clinical Use[edit | edit source]

Levopropoxyphene is used for the relief of mild to moderate pain. It is often used in combination with acetaminophen or aspirin for the treatment of pain and inflammation. Levopropoxyphene is also used in the treatment of cough, as it has antitussive properties.

Side Effects[edit | edit source]

Common side effects of levopropoxyphene include dizziness, nausea, vomiting, and constipation. Serious side effects can include respiratory depression, seizures, and addiction. Levopropoxyphene has a high risk of overdose, especially when combined with other central nervous system depressants such as alcohol or benzodiazepines.

Contraindications[edit | edit source]

Levopropoxyphene is contraindicated in patients with a history of hypersensitivity to propoxyphene or other opioids. It is also contraindicated in patients with significant respiratory depression, acute or severe bronchial asthma, or hypercapnia.

See Also[edit | edit source]

Resources[edit source]

Latest articles - Levopropoxyphene

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