Lipid pneumonia

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Lipid pneumonia is a specific form of lung disease that occurs when lipids enter the bronchial tree. This condition is a type of pneumonia that results from the presence of lipids in the lung. It can be either exogenous, where the lipids are introduced from outside the body, or endogenous, where the lipids originate from within the body.

Causes[edit | edit source]

Exogenous lipid pneumonia (ELP) is caused by the inhalation or aspiration of various types of oil-based substances, such as petroleum jelly, mineral oil, and vegetable oils. This can occur in a variety of situations, such as accidental aspiration, occupational exposure, or certain medical procedures.

Endogenous lipid pneumonia (ENLP), also known as cholesterol pneumonia or golden pneumonia, is caused by the accumulation of lipids within the lungs that originate from within the body. This can occur due to a variety of conditions, such as certain lung diseases, tumors, or lipid storage disorders.

Symptoms[edit | edit source]

The symptoms of lipid pneumonia can vary widely and may include cough, fever, chest pain, shortness of breath, and weight loss. In some cases, the condition may be asymptomatic and only discovered incidentally during a radiographic imaging study.

Diagnosis[edit | edit source]

The diagnosis of lipid pneumonia is often challenging due to its nonspecific symptoms and the fact that it can mimic other lung diseases on imaging studies. The diagnosis is usually confirmed by a lung biopsy, which shows the presence of lipid-laden macrophages in the lung tissue.

Treatment[edit | edit source]

The treatment of lipid pneumonia primarily involves addressing the underlying cause of the condition. This may involve discontinuing the use of the offending oil-based substance in cases of ELP, or treating the underlying condition causing ENLP. In some cases, corticosteroids may be used to reduce inflammation in the lungs.

See also[edit | edit source]

Lipid pneumonia Resources
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Contributors: Prab R. Tumpati, MD